most important research paper

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Collection  10 March 2022

Journal Top 100

This collection highlights our most downloaded* research papers published in 2021. Featuring authors from around the world, these papers highlight valuable research from an international community.

*Data obtained from SN Insights which is based on Digital Science’s Dimensions.

A well-trained artificial neural network for predicting the rheological behavior of MWCNT–Al 2 O 3 (30–70%)/oil SAE40 hybrid nanofluid

• Mohammad Hemmat Esfe
• S. Ali Eftekhari
• Davood Toghraie

More than 50 long-term effects of COVID-19: a systematic review and meta-analysis

• Sandra Lopez-Leon
• Talia Wegman-Ostrosky
• Sonia Villapol

Adults who microdose psychedelics report health related motivations and lower levels of anxiety and depression compared to non-microdosers

• Joseph M. Rootman
• Pamela Kryskow

Detection of persistent SARS-CoV-2 IgG antibodies in oral mucosal fluid and upper respiratory tract specimens following COVID-19 mRNA vaccination

• Aubree Mades
• Prithivi Chellamathu
• Albina Ibrayeva

Causes of death and comorbidities in hospitalized patients with COVID-19

• Sefer Elezkurtaj
• Selina Greuel
• David Horst

5G as a wireless power grid

• Jimmy G. D. Hester
• Manos M. Tentzeris

Saliva is more sensitive than nasopharyngeal or nasal swabs for diagnosis of asymptomatic and mild COVID-19 infection

• Alvin Kuo Jing Teo
• Yukti Choudhury
• Li Yang Hsu

Mathematical modelling of SARS-CoV-2 variant outbreaks reveals their probability of extinction

• Henrik Schiøler
• Torben Knudsen
• Martin Bøgsted

Mapping the NFT revolution: market trends, trade networks, and visual features

• Matthieu Nadini
• Laura Alessandretti
• Andrea Baronchelli

Overcooling of offices reveals gender inequity in thermal comfort

• Thomas Parkinson
• Stefano Schiavon
• Gail Brager

Clinical course of COVID-19 patients needing supplemental oxygen outside the intensive care unit

• Ayham Daher
• Paul Balfanz
• Christian G. Cornelissen

Positive effects of COVID-19 lockdown on air quality of industrial cities (Ankleshwar and Vapi) of Western India

• Ritwik Nigam
• Kanvi Pandya
• Mahender Kotha

Proportion of people identified as transgender and non-binary gender in Brazil

• Giancarlo Spizzirri
• Raí Eufrásio
• Carmita Helena Najjar Abdo

Immunodominant T-cell epitopes from the SARS-CoV-2 spike antigen reveal robust pre-existing T-cell immunity in unexposed individuals

• Swapnil Mahajan
• Vasumathi Kode
• Amitabha Chaudhuri

Positive expectations predict improved mental-health outcomes linked to psychedelic microdosing

• L. S. Kaertner
• M. B. Steinborn
• R. L. Carhart-Harris

Effect of vitamin D on cognitive decline: results from two ancillary studies of the VITAL randomized trial

• Jae H. Kang
• Chirag M. Vyas
• JoAnn E. Manson

Low HDL and high triglycerides predict COVID-19 severity

• Lluís Masana
• Eudald Correig
• the STACOV-XULA research group

Shorter headed dogs, visually cooperative breeds, younger and playful dogs form eye contact faster with an unfamiliar human

• Zsófia Bognár
• Enikő Kubinyi

Cannabis compounds exhibit anti-inflammatory activity in vitro in COVID-19-related inflammation in lung epithelial cells and pro-inflammatory activity in macrophages

• Seegehalli M. Anil
• Nurit Shalev
• Hinanit Koltai

The first true millipede—1306 legs long

• Paul E. Marek
• Bruno A. Buzatto
• Juanita Rodriguez

The poor prognosis and influencing factors of high D-dimer levels for COVID-19 patients

• Xiaokang He
• Qingming Wu

Pruritus is common in patients with chronic liver disease and is improved by nalfurafine hydrochloride

• Shuhei Yoshikawa
• Takeharu Asano
• Hirosato Mashima

Lethal coalitionary attacks of chimpanzees ( Pan troglodytes troglodytes ) on gorillas ( Gorilla gorilla gorilla ) in the wild

• Lara M. Southern
• Tobias Deschner
• Simone Pika

Secondary bacterial infection in COVID-19 patients is a stronger predictor for death compared to influenza patients

• Noa Shafran
• Inbal Shafran
• Ella H. Sklan

SARS-CoV-2 virus transfers to skin through contact with contaminated solids

• Saeed Behzadinasab
• Alex W. H. Chin
• William A. Ducker

The in-vitro effect of famotidine on SARS-CoV-2 proteases and virus replication

• Madeline Loffredo
• Hector Lucero
• Ali H. Munawar

Ferritin is associated with the severity of lung involvement but not with worse prognosis in patients with COVID-19: data from two Italian COVID-19 units

• Francesco Carubbi
• Lia Salvati
• Davide Grassi

Outcomes of COVID-19 patients intubated after failure of non-invasive ventilation: a multicenter observational study

• Annalisa Boscolo
• Laura Pasin
• FERS, for the COVID-19 VENETO ICU Network

The consequences of COVID-19 on social interactions: an online study on face covering

• Marta Calbi
• Nunzio Langiulli
• Maria Alessandra Umiltà

Dogs distinguish human intentional and unintentional action

• Britta Schünemann
• Judith Keller
• Juliane Bräuer

Positive Epstein–Barr virus detection in coronavirus disease 2019 (COVID-19) patients

• Changzheng Chen

Alarming coastal vulnerability of the deltaic and sandy beaches of North Africa

• Abderraouf Hzami
• Essam Heggy
• Saâdi Abdeljaouad

Defining priority areas for blue whale conservation and investigating overlap with vessel traffic in Chilean Patagonia, using a fast-fitting movement model

• Luis Bedriñana-Romano
• Rodrigo Hucke-Gaete
• Daniel M. Palacios

Observation of rescue behaviour in wild boar ( Sus scrofa )

• Michaela Masilkova
• Miloš Ježek
• Hynek Burda

Time course of the sensitivity and specificity of anti-SARS-CoV-2 IgM and IgG antibodies for symptomatic COVID-19 in Japan

• Yuki Nakano
• Makoto Kurano
• Yutaka Yatomi

Multidisciplinary assessment of the Abbott BinaxNOW SARS-CoV-2 point-of-care antigen test in the context of emerging viral variants and self-administration

• Jennifer K. Frediani
• Joshua M. Levy
• Wilbur A. Lam

Regular intake of energy drinks and multivitamin supplements is associated with elevated plasma vitamin B6 levels in post-bariatric patients

• Martina Tynes
• Matthias Hepprich
• Katharina Timper

Aggressive behaviour is affected by demographic, environmental and behavioural factors in purebred dogs

• Salla Mikkola
• Milla Salonen
• Hannes Lohi

In vitro efficacy of artemisinin-based treatments against SARS-CoV-2

• Yuyong Zhou
• Kerry Gilmore
• Peter H. Seeberger

Anthropogenic drought dominates groundwater depletion in Iran

• Samaneh Ashraf
• Amir AghaKouchak

COVID-19 vaccines that reduce symptoms but do not block infection need higher coverage and faster rollout to achieve population impact

• David A. Swan
• Chloe Bracis
• Dobromir Dimitrov

A metabolomics comparison of plant-based meat and grass-fed meat indicates large nutritional differences despite comparable Nutrition Facts panels

• Stephan van Vliet
• James R. Bain
• Kim M. Huffman

Detection of volcanic unrest onset in La Palma, Canary Islands, evolution and implications

• José Fernández
• Joaquín Escayo
• Eumenio Ancochea

Internet memes related to the COVID-19 pandemic as a potential coping mechanism for anxiety

• Umair Akram
• Kamila Irvine
• Jennifer Drabble

A molecular test based on RT-LAMP for rapid, sensitive and inexpensive colorimetric detection of SARS-CoV-2 in clinical samples

• Catarina Amaral
• Wilson Antunes
• Catarina Pimentel

Country-level factors dynamics and ABO/Rh blood groups contribution to COVID-19 mortality

• Alfonso Monaco
• Ester Pantaleo
• Roberto Bellotti

Musical components important for the Mozart K448 effect in epilepsy

• Robert J. Quon
• Michael A. Casey
• Barbara C. Jobst

Investigation of diets associated with dilated cardiomyopathy in dogs using foodomics analysis

• Caren E. Smith
• Laurence D. Parnell
• Lisa M. Freeman

Earliest evidence of herd-living and age segregation amongst dinosaurs

• Adriana C. Mancuso
• Vincent Fernandez

Canadian undergraduate men’s visual attention to cisgender women, cisgender men, and feminine trans individuals

• Lanna J. Petterson
• Paul L. Vasey

Brain structure changes associated with sexual orientation

• Mikhail Votinov
• Katharina S. Goerlich

Extreme miniaturization of a new amniote vertebrate and insights into the evolution of genital size in chameleons

• Jörn Köhler
• Miguel Vences

COVID-19 vaccine acceptance among adults in four major US metropolitan areas and nationwide

• Ayman El-Mohandes
• Trenton M. White
• Jeffrey V. Lazarus

Weeklong improved colour contrasts sensitivity after single 670 nm exposures associated with enhanced mitochondrial function

• Harpreet Shinhmar
• Glen Jeffery

Modeling the effect of lockdown timing as a COVID-19 control measure in countries with differing social contacts

• Tamer Oraby
• Michael G. Tyshenko
• Mustafa Al-Zoughool

Identification of CRF89_BF, a new member of an HIV-1 circulating BF intersubtype recombinant form family widely spread in South America

• Elena Delgado
• Aurora Fernández-García
• Michael M. Thomson

Selective time-dependent changes in activity and cell-specific gene expression in human postmortem brain

• Fabien Dachet
• James B. Brown
• Jeffrey A. Loeb

Effects of cannabis on visual function and self-perceived visual quality

• Sonia Ortiz-Peregrina
• Carolina Ortiz
• Rosario G. Anera

Particulate matter (PM 2.5 ) as a potential SARS-CoV-2 carrier

• Norefrina Shafinaz Md Nor
• Chee Wai Yip
• Mohd Shahrul Mohd Nadzir

The effect of ABO blood group and antibody class on the risk of COVID-19 infection and severity of clinical outcomes

• Marwa Ali Almadhi
• Abdulkarim Abdulrahman
• Manaf AlQahtani

A retrospective cohort study of 12,306 pediatric COVID-19 patients in the United States

• Vibhu Parcha
• Katherine S. Booker
• Pankaj Arora

Climate and the spread of COVID-19

• Simiao Chen
• Klaus Prettner
• David E. Bloom

Examining the interplay between face mask usage, asymptomatic transmission, and social distancing on the spread of COVID-19

• Adam Catching
• Sara Capponi
• Raul Andino

Association between coffee and green tea intake and pneumonia among the Japanese elderly: a case-control study

• Kyoko Kondo
• Kanzo Suzuki
• The Pneumonia in Elderly People Study Group

Discovery of a new mammal species (Soricidae: Eulipotyphla) from Narcondam volcanic island, India

• Manokaran Kamalakannan
• Chandrakasan Sivaperuman
• Kailash Chandra

Role of IgG against N-protein of SARS-CoV2 in COVID19 clinical outcomes

• Mayank Batra
• Runxia Tian
• Mehdi Mirsaeidi

Menopause impacts human brain structure, connectivity, energy metabolism, and amyloid-beta deposition

• Lisa Mosconi
• Valentina Berti
• Roberta Diaz Brinton

Ivermectin reduces in vivo coronavirus infection in a mouse experimental model

• A. P. Arévalo

Excess protein enabled dog domestication during severe Ice Age winters

• Maria Lahtinen
• David Clinnick
• Suvi Viranta

Psychedelics alter metaphysical beliefs

• Christopher Timmermann
• Hannes Kettner
• Robin L. Carhart-Harris

Real world evidence of calcifediol or vitamin D prescription and mortality rate of COVID-19 in a retrospective cohort of hospitalized Andalusian patients

• Carlos Loucera
• María Peña-Chilet
• Jose Manuel Quesada Gomez

Exercise improves the quality of slow-wave sleep by increasing slow-wave stability

• Insung Park
• Javier Díaz
• Kaspar E. Vogt

Gradual onset of the Maunder Minimum revealed by high-precision carbon-14 analyses

• Hiroko Miyahara
• Fuyuki Tokanai
• Hideyuki Hotta

Results of an early second PCR test performed on SARS-CoV-2 positive patients may support risk assessment for severe COVID-19

• Barak Mizrahi
• Maytal Bivas-Benita
• Gabriel Chodick

Satellite mega-constellations create risks in Low Earth Orbit, the atmosphere and on Earth

• Aaron C. Boley
• Michael Byers

Influenza vaccination and the risk of COVID-19 infection and severe illness in older adults in the United States

• Kelly Huang
• Shu-Wen Lin
• Chi-Chuan Wang

New spinosaurids from the Wessex Formation (Early Cretaceous, UK) and the European origins of Spinosauridae

• Chris T. Barker
• David W. E. Hone
• Neil J. Gostling

Expansion and characterization of epithelial stem cells with potential for cyclical hair regeneration

• Makoto Takeo
• Kyosuke Asakawa
• Takashi Tsuji

Durability of antibody response to vaccination and surrogate neutralization of emerging variants based on SARS-CoV-2 exposure history

• Thomas W. McDade
• Alexis R. Demonbreun
• Elizabeth M. McNally

Multiwave pandemic dynamics explained: how to tame the next wave of infectious diseases

• Giacomo Cacciapaglia
• Corentin Cot
• Francesco Sannino

An international comparison of age and sex dependency of COVID-19 deaths in 2020: a descriptive analysis

• Peter Bauer
• Jonas Brugger
• Martin Posch

Organic matter and water from asteroid Itokawa

• Q. H. S. Chan
• A. Stephant
• M. M. Grady

Origin and evolutionary history of domestic chickens inferred from a large population study of Thai red junglefowl and indigenous chickens

• Mitsuo Nunome
• Kornsorn Srikulnath

COVID-19 diagnosis by routine blood tests using machine learning

• Matjaž Kukar
• Gregor Gunčar
• Marko Notar

The serotonin reuptake inhibitor Fluoxetine inhibits SARS-CoV-2 in human lung tissue

• Melissa Zimniak
• Luisa Kirschner
• Jochen Bodem

Long-term stress in dogs is related to the human–dog relationship and personality traits

• Amanda Höglin
• Enya Van Poucke
• Lina S. V. Roth

Correlation between CT findings and outcomes in 46 patients with coronavirus disease 2019

• Guangming Li
• Guihua Jiang

Inhibition of mitochondrial function by metformin increases glucose uptake, glycolysis and GDF-15 release from intestinal cells

• Tamana Darwish
• Fiona M. Gribble

Global prevalence of mental health issues among the general population during the coronavirus disease-2019 pandemic: a systematic review and meta-analysis

• Surapon Nochaiwong
• Chidchanok Ruengorn
• Tinakon Wongpakaran

Probenecid inhibits SARS-CoV-2 replication in vivo and in vitro

• Jackelyn Murray
• Robert J. Hogan
• Ralph A. Tripp

UV-C irradiation is highly effective in inactivating SARS-CoV-2 replication

• Mara Biasin
• Andrea Bianco
• Mario Clerici

The 20-million-year old lair of an ambush-predatory worm preserved in northeast Taiwan

• Masakazu Nara
• Shahin E. Dashtgard

Age constraints for the Trachilos footprints from Crete

• Uwe Kirscher
• Haytham El Atfy
• Madelaine Böhme

Divergent reflections around the photon sphere of a black hole

• Albert Sneppen

The impact of the COVID-19 pandemic on wellbeing and cognitive functioning of older adults

• Sarah De Pue
• Céline Gillebert
• Eva Van den Bussche

Origin and diffusion of human Y chromosome haplogroup J1-M267

• Hovhannes Sahakyan
• Ashot Margaryan
• Richard Villems

The association of dietary patterns with dietary inflammatory index, systemic inflammation, and insulin resistance, in apparently healthy individuals with obesity

• Maryam Saghafi-Asl
• Susan Mirmajidi
• Vahideh Ebrahimzadeh Attari

Developing and validating COVID-19 adverse outcome risk prediction models from a bi-national European cohort of 5594 patients

• Espen Jimenez-Solem
• Tonny S. Petersen
• Martin Sillesen

COVID-19 in South Africa: outbreak despite interventions

• Malte Schröder
• Andreas Bossert
• Jan Schlüter

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